产品货号：
Z28321
中文名称：
TLR7抗体
英文名称：
Anti-TLR7 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TLR7 Antibody |
| 指标别名 | TLR7;toll like receptor 7 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC,FCM |
| 基因名称 | TLR7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human TLR7(1020-1038aa QAHPYFWQCLKNALATDNH),different from the related rat and mouse sequences by one amino acid. |
| 实际分子量 | 121KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TLR7(Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene.Orthologs are found in mammals and birds.TLR7 is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity.TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for the development of effective immunity.The various TLRs exhibit different patterns of expression.This gene is predominantly expressed in lung,placenta,and spleen,and lies in close proximity to another family member,TLR8,on human chromosome X.TLR7 recognises single stranded RNA in endosomes,which is a common feature of viral genomes which are internalised by macrophages. |
| Uniprot ID | Q9NYK1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | toll-like receptor 7 |
| 蛋白名全称 | Toll-like receptor 7 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 21 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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